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Prenatal testosterone leads to enough time-name behavioral changes in men zebra finches: unravelling the neurogenomic mechanisms

Maternal hormones, particularly testosterone, can be strongly dictate development young children, even promoting enough time-title business effects into mature choices; but really, the brand new mechanisms assisting this type of effects are still unclear. Right here, i experimentally raised prenatal testosterone on the egg out-of zebra finches (Taeniopygia guttata) and you can counted male aggression when you look at the adulthood in addition to habits regarding neural gene expression (RNA-seq) and you can DNA methylation (MethylC-Seq) in 2 socially related brain places (hypothalamus and you can nucleus taenia of your amygdala). We used enrichment analyses and protein-protein interaction systems to find applicant procedure and you can center genes probably impacted by the treatment. We concurrently understood differentially expressed genetics one contained differentially methylated places.

Overall performance

We learned amateurmatch iЕџe yarД±yor mu that people out of testosterone-injected eggs displayed way more aggressive practices as compared to men regarding handle egg. 继续阅读Prenatal testosterone leads to enough time-name behavioral changes in men zebra finches: unravelling the neurogenomic mechanisms